Resources & Evidence
GUIDELINES & EDUCATION
Center for Disease Control and Prevention
Nasal decolonization as a Staph Infection Prevention Strategy
Recommends nasal decolonization as a source control strategy to kill germs and prevent infections.
Health Research & Educational Trust (HRET)
Surgical Site Infections Change Package: 2018 Update
Recommends nasal decolonization to prevent surgical site infections caused by Staph aureus.
The Society for Healthcare Epidemiology of America (SHEA)
Compendium of Strategies to Prevent Healthcare-Associated Infections in Acute Care Hospitals
Recommends nasal decolonization for all patients in ICU and at high risk to prevent healthcare-associated infections.
Center for Disease Control and Prevention
The Nose as a Source of Germs
Per the CDC, “germs can get into the body through the eyes, nose and mouth and make us sick.”
WHITE PAPERS & ARTICLES
Becker’s Hospital Review
Increased Risk of HAIs and the Case for Patient Decolonization in the COVID-19 Era
Nasal decolonization for all patients reduces the risk of healthcare-associated infections (HAIs).
Outpatient Surgery Magazine
Nasal Decolonization Helps Control COVID-19
Nasal decolonization should be part of a multifaceted approach to infection prevention in surgical settings to protect staff and patients from infection.
Infection Control Today®
Nasal Decolonization and HAI Prevention: Applications and Evidence
Nasal decolonization demonstrated to be an effective healthcare-associated infection (HAI) prevention and control measure.
CLINICAL EVIDENCE
American Journal of Infection Control
A Safer, Less Costly SSI Prevention Protocol-Universal Versus Targeted Preoperative Decolonization
Decolonization for all hip and knee replacement surgical patients reduced the infection rate to zero and saved $400K in healthcare costs.
Infection Control & Hospital Epidemiology
Effectiveness of an Alcohol-Based Nasal Antiseptic in Reducing MRSA Bacteremia in an Adult Intensive Care Population
Use of alcohol-based nasal antiseptic reduced rate of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia to zero.
Open Forum Infectious Diseases
Does Universal Nasal Decolonization with an Alcohol-Based Nasal Antiseptic Reduce Infection Risk and Cost?
Hospital-wide application of alcohol-based nasal antiseptic resulted in a 100% decrease in MRSA surgical infections and over $104K costs avoided.
American Journal of Infection Control
Perioperative Participation of Orthopedic Patients and Surgical Staff in a Nasal Decolonization Intervention To Reduce Surgical Site Infections
Nasal decolonization with alcohol-based nasal antiseptic reduced surgical infection rates reduced by 81%.
Anesthesia & Analgesia®
Perioperative COVID-19 Defense: An Evidence-Based Approach for Optimization of Infection Control and Operating Room Management
An evidence-based approach to infection prevention for surgical patients should include nasal decolonization.
American Journal of Infection Control
Reduction of nasal Staph aureus carriage in Health Care Professionals by Treatment with a Nonantibiotic, Alcohol-based Nasal Antiseptic
Alcohol-based nasal antiseptic reduced nasal bacteria by 99% in health care professionals.
The New England Journal of Medicine
Targeted versus Universal Decolonization to Prevent ICU Infection
Nasal decolonization for all patients, together with daily antiseptic bathing, reduced ICU infections by 44%.