Resources & Evidence

GUIDELINES & EDUCATION

Center for Disease Control and Prevention

Nasal decolonization as a Staph Infection Prevention Strategy

Recommends nasal decolonization as a source control strategy to kill germs and prevent infections.

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Health Research & Educational Trust (HRET)

Surgical Site Infections Change Package: 2018 Update

Recommends nasal decolonization to prevent surgical site infections caused by Staph aureus.

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The Society for Healthcare Epidemiology of America (SHEA)

Compendium of Strategies to Prevent Healthcare-Associated Infections in Acute Care Hospitals

Recommends nasal decolonization for all patients in ICU and at high risk to prevent healthcare-associated infections.

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Center for Disease Control and Prevention

The Nose as a Source of Germs

Per the CDC, “germs can get into the body through the eyes, nose and mouth and make us sick.”

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WHITE PAPERS & ARTICLES

Becker’s Hospital Review

Increased Risk of HAIs and the Case for Patient Decolonization in the COVID-19 Era

Nasal decolonization for all patients reduces the risk of healthcare-associated infections (HAIs).

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Outpatient Surgery Magazine

Nasal Decolonization Helps Control COVID-19

Nasal decolonization should be part of a multifaceted approach to infection prevention in surgical settings to protect staff and patients from infection.

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Infection Control Today®

Nasal Decolonization and HAI Prevention: Applications and Evidence

Nasal decolonization demonstrated to be an effective healthcare-associated infection (HAI) prevention and control measure.

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CLINICAL EVIDENCE

American Journal of Infection Control

A Safer, Less Costly SSI Prevention Protocol-Universal Versus Targeted Preoperative Decolonization

Decolonization for all hip and knee replacement surgical patients reduced the infection rate to zero and saved $400K in healthcare costs.

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Infection Control & Hospital Epidemiology

Effectiveness of an Alcohol-Based Nasal Antiseptic in Reducing MRSA Bacteremia in an Adult Intensive Care Population

Use of alcohol-based nasal antiseptic reduced rate of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia to zero.

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Open Forum Infectious Diseases

Does Universal Nasal Decolonization with an Alcohol-Based Nasal Antiseptic Reduce Infection Risk and Cost?

Hospital-wide application of alcohol-based nasal antiseptic resulted in a 100% decrease in MRSA surgical infections and over $104K costs avoided.

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American Journal of Infection Control

Perioperative Participation of Orthopedic Patients and Surgical Staff in a Nasal Decolonization Intervention To Reduce Surgical Site Infections

Nasal decolonization with alcohol-based nasal antiseptic reduced surgical infection rates reduced by 81%.

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Anesthesia & Analgesia®

Perioperative COVID-19 Defense: An Evidence-Based Approach for Optimization of Infection Control and Operating Room Management

An evidence-based approach to infection prevention for surgical patients should include nasal decolonization.

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American Journal of Infection Control

Reduction of nasal Staph aureus carriage in Health Care Professionals by Treatment with a Nonantibiotic, Alcohol-based Nasal Antiseptic

Alcohol-based nasal antiseptic reduced nasal bacteria by 99% in health care professionals.

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The New England Journal of Medicine

Targeted versus Universal Decolonization to Prevent ICU Infection

Nasal decolonization for all patients, together with daily antiseptic bathing, reduced ICU infections by 44%.

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